Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MIR17 microRNA 17 0.459 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IMP3 Q9NV31 IMP U3 small nucleolar ribonucleoprotein 3 Nucleic acid binding 1.5E-07 0.566 0.462
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
HMMR O75330 hyaluronan mediated motility receptor 5.5E-21 0.544 0.615
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808